See DSM-5-TR for full diagnostic criteria

A. Two or more of the following, each present for a significant portion of time during a 1-month period (or less if successfully treated). At least 1 of these must be (1), (2), or (3): 
  1. Delusions 
  2. Hallucinations 
  3. Disorganized speech (eg, frequent derailment or incoherence) 
  4. Grossly disorganized or catatonic behavior 
  5. Negative symptoms (ie, diminished emotional expression or avolition) 
B. For a significant portion of the time since the onset of the disturbance, level of functioning in 1 or more areas (eg, work, interpersonal relations, or self-care) is markedly below the level achieved prior to the onset (or when the onset is in childhood or adolescence, there is a failure to achieve expected level of interpersonal, academic, or occupational functioning). 

C. Continuous signs of disturbance persist for at least 6 months. This 6-month period must include at least 1 month of symptoms (or less if successfully treated) that meet Criterion A and may include periods of prodromal or residual symptoms. During these prodromal or residual periods, the signs of the disturbance may be manifested by only negative symptoms or by 2 or more symptoms listed in Criterion A present in an attenuated form (eg, odd beliefs, unusual perceptual experiences). 

D. Schizoaffective disorder and depressive or bipolar disorder with psychotic features have been ruled out because either (1) no major depressive or manic episodes have occurred concurrently with the active-phase symptoms, or (2) if mood episodes have occurred during active-phase symptoms, they have been present for a minority of the total duration of the active and residual periods of the illness. 

E. The disturbance is not attributable to the physiological effects of a substance (eg, a drug of abuse, a medication) or another medical condition.

F. If there is a history of autism spectrum disorder or a communication disorder of childhood onset, the additional diagnosis of schizophrenia is made only if prominent delusions or hallucinations, in addition to the other required symptoms of schizophrenia, are also present for at least 1 month (or less if successfully treated). 

Please see DSM-5-TR for full diagnostic criteria.

  1. American Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders. DSM-5-TR. 5th ed. Arlington, VA: American Psychiatric Association; 2022.